INTRATHECAL MORPHINE IS ASSOCIATED WITH REDUCTION IN POSTOPERATIVE OPIOID REQUIREMENTS AND IMPROVEMENT IN POSTOPERATIVE ANALGESIA IN PATIENTS UNDERGOING OPEN LIVER RESECTION

Intrathecal morphine is associated with reduction in postoperative opioid requirements and improvement in postoperative analgesia in patients undergoing open liver resection

Abstract Background Our study aimed to test the hypothesis that the addition of intrathecal morphine (ITM) results in reduced postoperative opioid use and enhanced postoperative analgesia in patients undergoing open liver resection using a standardized enhanced recovery after surgery (ERAS) protocol with multimodal analgesia.Methods A retrospective

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How to build a cross-disciplinary institute: the curious case of the South American Institute for Resilience and Sustainability Studies

There is no recipe for setting up a new institute, especially if it is meant to be different from anything that currently exists.Here, we give a look behind the scenes at how we dreamt up the transdisciplinary South American Institute for Resilience and Sustainability Science (SARAS), located in Uruguay, and how, with help from a network of renowne

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For a renewed harm reduction model

Abstract In the early 1990s, the spread of HIV among heroin injectors prompted a shift in drug policy internationally, including in France.This led to the emergence of a new policy known as Harm Reduction (HR) and related tools, including needle exchange programmes, opioid substitution therapy programmes to manage illicit opiate consumption, as wel

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